MONROVIA, CA – Dr. Samir Hanash, Program Head at Fred Hutchinson Cancer Research Center will give the keynote presentation at GTCbio’s 2nd Annual Rediscovering Biomarkers Conference on July 10-11, 2008 in Boston, MA. Dr. Hanash will be presenting on “Fast Tracking the Development of Cancer Biomarkers.”

Although our understanding of the molecular pathogenesis of common types of cancers has improved considerably, the development of effective strategies for cancer diagnosis and treatment have lagged behind. Circulating proteins are an important source of cancer diagnostics. However the vast dynamic range of protein abundance in plasma and the likely occurrence of tumor derived proteins in the lower range of protein abundance represent a major challenge in applying a proteomic based strategy for their identification. A combination of innovative strategies promises to overcome these challenges. Recent experience in comprehensive profiling of plasma proteins indicates that low abundance proteins may be identified and quantified with high confidence following extensive plasma fractionation and high-resolution mass spectrometry. From an experimental design point of view, for discovery of early detection markers, a preferred approach is to utilize plasma obtained at a pre-clinical stage, prior to the diagnosis of cancer. Another implementation of this approach is through the use of mouse models of cancer that potentially represent an efficient means for uncovering diagnostic markers that occur early during tumor development. Yet another approach is to identify tumor antigens that induce a humoral response that can be assessed based on seropositivity. Implementation of these approaches has resulted in the identification of potential markers for early cancer detection

The 2nd Annual Rediscovering Biomarkers Conference will exposes attendees to the latest advancements and developments in biomarkers and predictive medicine. Attendees will gain insight into discovery and development processes, hear about new biomarkers and upcoming trends in the industry, as well as the status of those in clinical trials. Delegates will also receive highly valuable information on tools for improving reimbursement strategies and the efficacy and validation of biomarkers.

For more information including a detailed agenda, exhibitor opportunities and registration information visit http://gtcbio.com/conferenceDetails.aspx?id=124
ABOUT GTCbio
GTCbio organizes conferences specifically for the biomedical and biopharmaceutical industries. Our goal is to facilitate the exchange of biopharmaceutical and biomedical intelligence between industry leaders, academic and government organizations, and the financial community.
GTCbio is a subsidiary of Global Technology Community, LLC, a privately held company founded in 2002.
Contact: GTCBIO (626) 256-6405, (626) 256-6460 fax, infogtcbio@gtcbio.com

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